Aluminum zirconate nanoparticles in etch and rinse adhesive to caries affected dentine: An in-vitro scanning electron microscopy, elemental distribution, antibacterial, degree of conversion and micro-tensile bond strength assessment.

To incorporate different concentrations of Al2O9Zr3 (1%, 5%, and 10%) nanoparticles (NP) into the ER adhesive and subsequently assess the impact of this addition on the degree of conversion, µTBS, and antimicrobial efficacy. The current research involved a wide-ranging examination that merged various investigative techniques, including the application of scanning electron microscopy (SEM) for surface characterization of NP coupled with energy-dispersive x-ray spectroscopy (EDX), Fourier-transform infrared (FTIR) spectroscopy, µTBS testing, and microbial analysis. Teeth were divided into four groups based on the application of modified and unmodified three-step ER adhesive primer. Group 1 (0% Al2O9Zr3 NPs) Control, Group 2 (1% Al2O9Zr3 NPs), Group 3 (5% Al2O9Zr3 NPs), and Group 4 (10% Al2O9Zr3 NPs). EDX analysis of Al2O9Zr3 NPs was performed showing elemental distribution in synthesized NPs. Zirconium (Zr), Aluminum (Al), and Oxides (O2). After primer application, an assessment of the survival rate of Streptococcus mutans was completed. The FTIR spectra were analyzed to observe the characteristic peaks indicating the conversion of double bonds, both before and after the curing process, for the adhesive Etch and rinse containing 1,5,10 wt% Al2O9Zr3 NPs. µTBS and failure mode assessment were performed using a Universal Testing Machine (UTM) and stereomicroscope respectively. The µTBS and S.mutans survival rates comparison among different groups was performed using one-way ANOVA and Tukey post hoc (p = .05). Group 4 (10 wt% Al2O9Zr3 NPs + ER adhesive) specimens exhibited the minimum survival of S.mutans (0.11 ± 0.02 CFU/mL). Nonetheless, Group 1 (0 wt% Al2O9Zr3 NPs + ER adhesive) displayed the maximum surviving S.mutans (0.52 ± 0.08 CFU/mL). Moreover, Group 2 (1 wt% Al2O9Zr3 NPs + ER adhesive) (21.22 ± 0.73 MPa) samples displayed highest µTBS. However, the bond strength was weakest in Group 1 (0 wt% Al2O9Zr3 NPs + ER adhesive) (14.13 ± 0.32 MPa) study samples. The etch-and-rinse adhesive exhibited enhanced antibacterial activity and micro-tensile bond strength (µTBS) when 1% Al2O9Zr3 NPs was incorporated, as opposed to the control group. Nevertheless, the incorporation of Al2O9Zr3 NPs led to a decrease in DC. RESEARCH HIGHLIGHTS: 10 wt% Al2O9Zr3 NPs + ER adhesive specimens exhibited the minimum survival of S.mutans. 1 wt% Al2O9Zr3 NPs + ER adhesive samples displayed the most strong composite/CAD bond. The highest DC was observed in Group 1: 0 wt% Al2O9Zr3 NPs + ER adhesive.

A massive primary congenital mesoblastic nephroma was successfully managed through open total nephrectomy: a case report.

Background: Congenital mesoblastic nephroma is the most common renal tumor in children under the age of 6 months, comprising 3-10% of all kidney tumors in children. It is a rare and mostly benign tumor. It divides into cellular, classic, and mixed subtypes. It is typically detected in the third trimester of pregnancy using ultrasonography and magnetic resonance imaging. The best treatment is surgically by completely removing the tumor. Case presentation: We reported a case of a one-day-old female who was born at 31 weeks gestation weighing 1670 g. Preterm labor was due to polyhydramnios, which was diagnosed predelivery. A large mass was detected in the left hypochondrium using computerized tomography, total nephrectomy was performed, and the histopathological examination of the specimen confirmed the diagnosis of congenital mesoblastic nephroma. Clinical discussion and conclusion: Early polyhydramnios could be the most significant sign of renal tumors in infants, especially congenital mesoblastic nephroma.

Instructional illustrations in children's learning between normative and realism: An evaluation study.

Many studies indicate the importance of including the instructional illustrations (pictures, drawings, concrete objects …etc.) in childhood education learning materials and employing them in a way that suits the psychological and cognitive levels of young children. In this context, the current study aimed to develop a list of standards to be considered and adopted in designing instructional illustrations, and to reveal the perceptions of childhood teachers about the extent to which these standards are considered in instructional illustrations used in children's learning materials. The participants were childhood education teachers in the Jordanian region of Irbid, who were randomly selected. Two hundred thirty-four teachers completed the questionnaire online. The scale consisted of a total of 34 items distributed over four dimensions. The results showed that the scores of teachers' estimation about employing design standards in the instructional illustrations used in childhood education came at low levels, ranging from average to low, and did not reach high ratings. The study also revealed that there is an impact attributed to teaching experience on teachers' perceptions about the extent to which these standards are employed in instructional illustrations, while there is no impact of gender, academic qualification, or the classes taught by the teachers.

A Cross-Sectional Study on Self-Perceived Halitosis among Undergraduate University Students in Riyadh, Saudi Arabia.

Aim: The present cross-sectional observational study was conducted to evaluate the prevalence of halitosis among undergraduate university students at Riyadh Elm University, Riyadh, Saudi Arabia. Materials and Methods: A survey of 301 participants who answered a questionnaire on their self-perceived halitosis was undertaken. Results: The response rate was 35% (301/863). Of the total, 54.5% of participants reported that they had experienced halitosis. A majority of participants (61.4%) responded to having experienced an unpleasant bad taste in the morning when they woke up, with most participants (42.4%) stating that their breath was the worst early in the morning. A majority of respondents (59.6%) reported that they were aware of their condition. Only 27% of the respondents stated that they had admitted to having undergone an examination for bad breath from their dentist, and 22.9% of the respondents reported that they had undergone an examination for conditions associated with bad breath. The measures used to reduce the condition were evenly distributed, with approximately one-third using mouthwash (34.6%), gum/mentos (38.3%), and toothpaste (27.2%). Conclusion: The incidence of self-perceived halitosis that was revealed in the current study is normal compare to others studies. It is unrelated to age and sex. Non-usage of dental floss, no use of mouthwash, and smoking, on the other hand, were shown to be associated with self-perceived halitosis. Furthermore, tongue cleaning was not linked to introspection halitosis. Halitosis may be also due to underlying systemic conditions. Hence it is necessary to evaluate the condition's prevalence and examine the relationship with other etiological variables with halitosis in our country.

Photo-induced photoacoustic streaming and pineapple peel extract as final irrigant on extrusion bond strength of root filling material to canal wall.

Objective: Photon-induced photoacoustic streaming (PIPS) with pineapple peel extract (PPE) and ethylenediaminetetraacetic acid (EDTA) as a final endodontic irrigant on the push-out bond strength (PBS) of root filling material to conventional irrigation NaOCl with EDTA. Methods: An in vitro study at Dar Al Uloom University was conducted over three months. Root canal preparation was performed. Based on final irrigation, all the specimens were divided randomly into four groups (n=10) Group 1: 2.25% NaOCl+ 17% EDTA (control), Group-2: 2.25% NaOCl+PIPS + 6.25% PPE, Group-3: 2.25% NaOCl+PIPS + 17% EDTA, Group-4: 2.25% NaOCl + 6.25% PPE. Canals were obturated and sealed with AH Plus sealer. Root sectioning was performed at 1mm thickness and PBS testing was performed using the universal testing machine. The debonded samples were analyzed for failure mode. ANOVA compared the means and standard deviations (SD) of all investigated group. Assessment of multiple comparisons was performed using Tukey's post hoc test. Results: The maximum PBS was demonstrated by the coronal section of Group-2 (2.25%NaOCl +PIPS+6.25%PPE) specimens (8.21±0.81MPa). The apical section of Group-1 (2.25% NaOCl+17% EDTA) specimens demonstrated minimum bond strength (2.80±0.18 MPa). The intergroup comparison revealed that Group-3 (2.25% NaOCl +PIPS +17% EDTA) and Group-2 demonstrated comparable outcomes (p>0.05). Group-4 (2.25% NaOCl +6.25% PPE) specimens established significantly lower values than Group-3 and Group-4 (p<0.05). Conclusion: Photon-induced photoacoustic streaming with pineapple peel extract and EDTA demonstrated better bond strength of root canal sealer and have the potential to be used as the final irrigant.

Use of final irrigants MTAD, Salvedora Perscia, Malachite green, and Ti-sapphire laser on push-out bond strength of Zirconia post.

AIM: Evaluation of the push-out bond strength (PBS) of zirconia post-bonded to radicular dentin after using different final irrigants (MTAD, Malachite green (MG), Ti-sapphire laser and Salvadora persica (S.persica). MATERIAL AND METHOD: Forty human permanent single-rooted were decoronated above the cement-enamel junction. An experienced endodontist performed all the root canal instrumentation using ProTaper universal rotary files. Canals were irrigated using 5.25% NaOCl solution followed by EDTA as a final sterilant. Obturation with gutta-percha using AH Plus sealer was performed. Post-space preparation was completed using Gates Glidden and specimens were randomly assigned to four groups based on the final disinfectant received (n=10). Group 1: 5.25% NaOCl + MTAD, group 2: 5.25% NaOCl + MG, group 3: 5.25% NaOCl +Ti-sapphire laser, and group 4: 5.25% NaOCl + S. persica. The chemically polymerized resin was used to lute zirconia posts. PBS and failure mode analysis were performed using a universal testing machine and stereomicroscope at 40X magnification. Data were compared between the two groups with 95% CI using one-way analysis of variance (ANOVA) with the Tukey post hoc test. p=0.05. RESULTS: Group4(5.25% NaOCl+ S.persica) specimens demonstrated the maximum (8.94±0.14 MPa) bond strength. Conversely, the apical third of Group 2 (5.25% NaOCl+ MG) (2.87±0.15 MPa) samples revealed the minimum bond strength scores. Intergroup comparison exposed that Group 1 (1.3% NaOCl+ MTAD), Group 3 (5.25% NaOCl+Ti-sapphire laser), and Group 4 (5.25% NaOCl+ S. persica) at all three-thirds unveiled no significant difference in PBS (p<0.05). CONCLUSION: Ti-sapphire laser and Salvedora Persica possess the potential to be used as a final root canal irrigant to improve the push-out bond strength of zirconia post-to-root dentin.

Micro Tensile bond strength and microleakage assessment of total-etch and self-etch adhesive bonded to carious affected dentin disinfected with Chlorhexidine, Curcumin, and Malachite green.

AIMS AND OBJECTIVES: Assessment of micro tensile bond strength (microTBS) and micro-leakage scores of total-etch adhesive (TAE) and self-etch adhesive (SAE) bonded to carious affected dentin (CAD) sterilized using different cavity disinfectant (curcumin photosensitizer (CP) and malachite green (MG) and Chlorhexidine (CHX) in comparison to no disinfection (ND) control group. MATERIALS AND METHODS: One hundred and twenty human molars having International Caries Detection and Assessment System (ICDAS) scores of 4 and 5 were included. Visual inspection, dental explorer hardness testing, and caries detector solution using 5% basic Fuchsin dye solution was applied to dentin to identify the CAD surface. All the specimens were divided into four groups (n = 30) according to the cavity disinfectants used. Group A: 2% CHX, Group B: CP, Group C: MG, and Group D: ND. Each group was further divided into two subgroups (n = 15) based on the adhesion protocol. Groups A1, B1, C1, and D1 were held using TEA, and groups A2, B2, C2, and D2 were adhered using SEA system. The composite material was then built in 2 mm increments and then cured with light. MicroTBS and failure mode assessment using a universal testing machine (UTM) and stereomicroscope at a 40X magnification was performed on 10 samples from each subgroup. The microleakage assessment was performed using a dye penetration test on five samples from each group. ANOVA and Tukey post-hoc tests were used to compare means and standard deviation (SD) of bond strength and microleakage (p < 0.05). RESULTS The maximum microTBS was displayed by A1= CHX and TEA (13.28± 1.01 MPa). The lowest bond scores were demonstrated by C2= MG and SEA (5.98±0.44 MPa). The highest micro-leakage was exhibited by C1= MG and TEA (58.32 ± 2.11 nm). Whereas, the lowest micro-leakage values were displayed by A2= CHX and SEA (24.34± 1.11 nm). CONCLUSION: Chlorohexidiene displayed better bond strength and the lowest microleakage scores with Total-etch adhesive and Self-etch adhesives when used as a cavity disinfectant. Total-etch adhesives performed better in terms of microTBS scores whereas self-etch adhesives displayed superior seal ability within the same disinfectant group.

Different cavity disinfectant efficacy against S.mutans and shear bond strength of caries affected dentin bonded to resin restoration.

AIMS: The existing study aimed to assess the survival rate of S.mutans and shear bond strength (SBS) of resin adhesive restoration bonded to carious affected dentin (CAD) after using different cavity disinfectants (Chitosan, Fotoenticine®, and CO2 laser) in comparison to Chlorhexidine (CHX). MATERIALS AND METHODS: The study included human mandibular molars assessed on International Caries Detection and Assessment System (ICDAS) score 4 and 5. The cusp part of the clinical crown was cut off until the reduction reaches the central fossa while being continuously supplied with water coolant till the tooth cementoenamel junction (CEJ). The root sections were embedded in polymethyl methacrylate acrylic resin followed by culturing S.mutans biofilm on the CAD surface. Specimens were arbitrarily allocated into four groups(n = 10) based on the type of disinfection. Group 1 (2% CHX), Group 2 (Chitosan), Group 3 (Fotoenticine), and Group 4 (CO2 laser). S.mutans survival rate was assessed and CAD was restored with a composite restorative material. Thermoocycling of the samples was performed and a universal testing machine (UTM) and Stereomicroscope were used to identify bond integrity and type of fracture. ANOVA and Tukey multiple comparison tests were used to assess SBS. Data on the survival rate of S. mutans were compared between groups using the nonparametric Kruskal-Wallis test RESULTS: Outcomes revealed that Group 1 (CHX) displayed the highest survival rate (0.65 ± 0.10). However, lowest survival rate was demonstrated by Group 3 (Fotoenticine) treated specimens (0.25 ± 0.06). It was also discovered that CHX unveiled highest bond strength values (21.48 ± 1.39 MPa). Nevertheless, Group 2 (Chitosan) showed lowest SBS (11.01 ± 1.00 MPa). Intergroup comparison analysis presented that group 1, and group 4 (Co2 laser) (17.76 ± 0.41 MPa) displayed no significant difference in their bond integrity achieved. (p > 0.05). However, group 3 (Fotoenticine) (16.28 ± 0.51 MPa) and group 2 demonstrated comparable outcomes of SBS. (p > 0.05) CONCLUSION: The use of CHX and CO2 lasers as disinfectants on the CAD surface resulted in a positive impact on the SBS of resin composite, according to the study's findings. However, it is worth noting that Fotoenticine exhibited better antimicrobial efficacy against S. mutans.

Effectiveness of Morinda citrofolia, Sapindus mukorossi, and curcumin used in curry spice, to the radicular canal irrigant in improving bond integrity of glass fiber post.

AIM: Evaluation of the push-out bond strength (PBS) of glass fiber reinforced post (GFRP) bonded to root dentin after canal disinfection using food-based root canal irrigants i.e., Curcumin photosensitizer (CP), Riboflavin photosensitizer (RFP), Morinda ctrifolia juice (MCJ) and Sapindus mukorossi (SM) along with MTAD as a final irrigant. MATERIAL METHODS: Fifty human single-rooted premolar teeth were decoronated. Endodontic preparation was performed along with 2.25% sodium hypochlorite NaOCl solution followed by EDTA solution. Canals were dried and obturated followed by post-space preparation by removing GP. Specimens were allocated into five groups based on different food-based disinfection regimes (n = 10). Group 1: 2.25% NaOCl + MTAD (Control), Group 2: 6% MCJ + MTAD, Group 3: SM + MTAD, Group 4: CP + MTAD and Group 5: RFP + MTAD. All GFRP were bonded to radicular dentin. Root sectioning was performed followed by PBS and failure analysis using a universal testing machine (UTM) and stereomicroscope respectively. The data were analyzed using a one-way analysis of variance (ANOVA) test and the Post Hoc Tukey HSD test (p = 0.05). RESULTS: Samples disinfected with(MCJ+MTAD) at coronal third demonstrated maximum PBS (9.41 ± 0.51 MPa). However, the apical third of group 5 (RFP + MTAD) exhibited the minimum values (4.06 ± 0.23 MPa). Intergroup comparison analysis unveiled that group 2 (MCJ +MTAD) and group 3 (SM+MTAD) displayed comparable outcomes of PBS at all three-thirds. Similarly, samples in group 1 (2.25% NaOCl + MTAD), group 4 (CP + MTAD), and group 5 (RFP + MTAD) exhibited comparable PBS. CONCLUSION: Fruit-based irrigants Morinda citrifolia and Sapindus mukorossi have the potential to be used as root canal irrigants with a positive influence on bond strength.

Role of female teachers of childhood education in directing children towards effective use of smart devices.

This study endeavors to investigate the role of female teachers of childhood education in directing children towards the effective use of smart devices in developing their learning experiences. The sample of the study consisted of 83 female teachers in the northern region of Jordan, who were selected using the available sampling method. To achieve the aim of the study, a semi-structured interview was prepared and its validity and consistency were verified. The results shown that childhood education female teachers achieved advanced roles in directing children towards the effective use of smart devices, where effective direction towards the use of smart devices was represented in: directing children to self-organize their learning during using smart devices, directing children to acquire digital social interaction skills and directing them to learn innovation during using smart devices, with the importance of directing them to avoid the harms of using smart devices through preventive guidance. Moreover, the findings of the study revealed the importance of directing children to participate in various digital activities, as well as directing them to learn through digital applications that are purposeful and suitable to their mental capabilities. Based on the research findings, the study presented a number of relevant recommendations.

Comparative efficacy of coronally advanced flap with and without guided tissue regeneration in the management of gingival recession defects: A split-mouth trial.

Background: The gingival recession causes tooth sensitivity, poor esthetics, and tooth mobility in severe cases. Scientific documentation revealed effective root coverage (RC) and increased keratinized tissue heights acquired with the coronally advanced flap (CAF) for multiple recession defects. Objectives: This research evaluates and compares the efficacy of CAF procedures with and without Type I collagen bio-absorbable membrane in guided tissue regeneration (GTR) in the treatment of Miller's Class I and II gingival recession. Materials and Methods: A total of 30 sites from 15 patients were selected for the study after fulfilling the presurgical phase of treatment. The chosen sites were randomly allocated into Group A CAF and Group B (CAF + Resorbable GTR membrane). The clinical variables such as plaque index, gingival index, recession depth (RD), recession width (RW), width of keratinized gingiva (WKG), clinical attachment level (CAL), and surface area of the defect were recorded at the baseline and 6 months postoperatively. Results: Both therapies resulted in a notable gain in RC with a mean of 73.13% and 71.60%, respectively, but it was not statistically significant when compared between the groups. Both the RD and RW were significantly reduced from baseline to 6 months postoperatively. Although there was a gain in WKG and CAL in both experimental sites, no significant difference was observed between both the groups. Conclusion: Although there are several RC procedures, CAF furnishes a foreseeable, straightforward, and appropriate perspective for treating Miller's Class I and II recessions. Integrating this approach with placing a bio-absorbable membrane does not seem to improve the results following surgical treatment of such defects. However, both groups showed the potential advantage of achieving RC.

Résumé Contexte: La récession gingivale provoque une sensibilité dentaire, une mauvaise esthétique et une mobilité dentaire dans les cas graves. La documentation scientifique a révélé une couverture efficace de la racine (RC) et une augmentation de la hauteur du tissu kératinisé acquises avec le lambeau coronalement avancé (CAF) pour de multiples défauts de récession multiples. Objectifs: Cette recherche évalue et compare l'efficacité des procédures CAF avec et sans membrane bio-absorbable de collagène de type I dans la régénération tissulaire guidée (RTC). de collagène de type I dans la régénération tissulaire guidée (RTG) dans le traitement de la récession gingivale de classe I et II de Miller. Matériaux et Méthodes: Un total de 30 sites de 15 patients ont été sélectionnés pour l'étude après avoir rempli la phase pré-chirurgicale du traitement. Les sites choisis ont été répartis au hasard dans le groupe A (CAF) et le groupe B (CAF + membrane GTR résorbable). Les variables cliniques telles que l'indice de plaque, l'indice gingival, la profondeur de la récession (RD), la largeur de la récession (GTR) ont été évaluées. gingivale, la profondeur de la récession (RD), la largeur de la récession (RW), la largeur de la gencive kératinisée (WKG), le niveau d'attachement clinique (CAL) et la surface du défaut. ont été enregistrés au début de l'étude et 6 mois après l'opération. Résultats: Les deux thérapies ont entraîné un gain notable de RC avec une moyenne de 73,13 % et 71,60 % respectivement. 71,60 %, respectivement, mais la comparaison entre les groupes n'était pas statistiquement significative. La RD et la RW ont toutes deux été réduites de manière significative de la ligne de base à 6 mois après l'opération. Bien qu'il y ait eu un gain en WKG et CAL dans les deux sites expérimentaux, aucune différence significative n'a été observée entre les deux groupes. observée entre les deux groupes. Conclusion: Bien qu'il existe plusieurs procédures de RC, la CAF fournit une perspective prévisible, directe et appropriée pour traiter la classe de Miller perspective prévisible, simple et appropriée pour traiter les récessions de classe I et II de Miller. L'intégration de cette approche avec la mise en place d'une membrane bio-absorbable ne semble pas améliorer les résultats après le traitement chirurgical. semble pas améliorer les résultats après le traitement chirurgical de ces défauts. Cependant, les deux groupes ont montré l'avantage potentiel de réaliser une RC. Mots-clés: Lambeau avancé coronaire, récession gingivale, régénération tissulaire guidée, chirurgie plastique parodontale, membrane résorbable.

Minimal Invasive Technique for the Esthetic Management of Dental Fluorosis.

Dental fluorosis is a severe dental extremity due to excess fluoride intake during enamel formation, resulting in color abnormalities and severe tooth defects on its surface. This dental condition leads to abnormal appearance ranging from mild white to dark brown, affecting the esthetic characteristics and personality of the patient that eventually lowers their self-confidence. Restoration procedures and tooth-whitening procedures are the well-appreciated treatment methods for treating this anomaly. The current clinical report illustrates the minimally invasive technique for esthetic management of dental fluorosis in a 27-year-old male affected by dental fluorosis. Clinical examination revealed dental fluorosis of class II spots according to Dean's classification of fluorosis severity. The treatment plan involves minimally invasive micro-abrasion, vital teeth bleaching, and resin infiltration technique for blending different microporous lesions, mild-to-moderate fluorosis, and hypoplasia stains.

Endocrowns Versus Post-core Retained Crowns as a Restoration of Root Canal Treated Molars - A Review Article.

Normally root canal-treated teeth are covered with crowns to prevent fracture, which becomes challenging in cases where the tooth is extensively damaged. In such instances, various restorative methods such as post-core and endocrowns have been in use. The former methodology in recent times is being discouraged owing to impending tooth weakening. Due to this reason, an uncommon type of reconstruction, endocrowns are preferred. We carried out a comparative review of restorations for endodontically treated molars.

A Case Report on Surgical-Orthodontic Correction of Skeletal Class III Malocclusion with Severe Prognathic Mandible and Retrognathic Maxilla.

Mandibular prognathism combined with a retrognathic maxilla is a skeletal discrepancy that is difficult to correct. We report a case of a 25-year-old Saudi male patient with skeletal class-III malocclusion due to severe prognathic mandible who was referred to an orthodontist at Prince Sultan Military Medical City. Complete clinical examination, radiographic assessment, and study models revealed class-III malocclusion due to anteroposterior deficiency of the maxilla and severe prognathic mandible. Orthognathic surgery was performed 18 months after the presurgical orthodontic phase. A 10-mm LeFort I advancement of the maxillary arch, with impaction of 3 mm, was performed with a bilateral sagittal split osteotomy (BSSO) of 11 mm. Stable occlusion and superior aesthetics were observed at the 1-year follow-up. Surgical-orthodontic treatment endows an adult patient with a class-III malocclusion or mandibular prognathism with a stable occlusion and superior aesthetics.

Disinfection of caries-affected dentin using potassium titanyl phosphate laser, Rose bengal and Ozonated water on shear bond strength of deciduous teeth.

AIM: To assess the efficacy of disinfection of caries-effected dentin (CAD) using KTP laser and different decontamination methods using ozonated water (OW), Rose Bengal photosensitizer (RBP), chlorhexidine (CHX), and Er, YAG laser on the shear bond strength (SBS) of adhesive resin bonded to deciduous teeth. MATERIAL AND METHODS: A total of 50 extracted and radiographically verified carious primary molars were collected and scrutinized according to ICDAS criteria. Specimens were allocated randomly into five groups (n = 10) as per the type of CAD disinfectants. KTP laser, OW, RBP, CHX (control), and Er, YAG laser. After cavity sanitization, a resin adhesive (prime and bond NT) was smeared on the dentinal exterior followed by incremental composite filling. SBS evaluation was performed by employing specimens in the universal testing machine. The debonded surface was assessed under 40x magnification in a stereomicroscope to ascertain fracture mode. Statistical analysis was done by using the ANOVA and the Post Hoc Tukey multiple comparison tests (p < 0.05). RESULTS: The highest SBS was exhibited by group 2 i.e., when OW was employed for CAD disinfection (10.25 ± 0.24 MPa). Whereas, the lowest SBS bond value was unveiled by samples in group 3 when RBP was applied for dentin surface sanitization (7.85 ± 0.59 MPa).CAD disinfection with KTP laser (8.25 ± 0.41 MPa), CHX (8.19 ± 0.73 MPa), and RBP displayed comparable bond values (p > 0.05). CONCLUSION: Ozonated water and Er, YAG laser could be employed as cavity disinfectants in primary teeth as they demonstrated better shear bond strength without jeopardizing the adhesive binding capacity of restorative resins bonded to caries-affected dentin.

Glass fiber post resistance to dislodgement from radicular dentin after using contemporary and conventional methods of disinfection.

AIM: The present study aimed to assess the bond integrity of curcumin photosensitizer (CPS) Photodynamic therapy (PDT) on fiber post disinfection bonded to radicular dentin in comparison to the conventional fiber post sterilant used. MATERIALS AND METHODS: Fifty human permanent single-rooted premolars were utilized with the crown part sectioned using up to the cementoenamel junction. Root canal preparation was performed followed by canal obturation with gutta-percha (GP) and resin-based sealer. The post space was prepared using peso reamers leaving 4 mm at the apical part of the post space. Fifty glass fiber posts (GFP) were divided into five groups based on the surface disinfectant (n = 10). group 1: Autoclave sterilization (AS) group 2: chlorhexidine digluconate (CHX dig), group 3: CPS solution, group 4: 35% phosphoric acid (PA) gel, and group 5: No disinfection. Cementation was performed using dual-cure self-etch resin cement. Each tooth was sectioned and placed on the universal testing machine. Failure mode was analyzed using a stereomicroscope at 40x magnification. Statistical analysis was performed using one-way analysis of variance (ANOVA) and Tukey multiple comparison tests. (p = 0.05). RESULTS: Intragroup comparison analysis demonstrated that group 2 in which 2% CHX dig was used as a post-surface disinfectant revealed the highest bond integrity at all three levels. Group 5 where no disinfectant was used to decontaminate the post surface exhibited the lowest bond values. In all the investigated groups, PBS values showed a downward trend from coronal to the apical third of the post space. Group 1 in which AS was used to sterilize the fiber post and group 3 in which CPS was smeared to decontaminate the GFPs surface-displayed comparable outcomes of PBS to group 5 specimens at all three levels. (p > 0.05). CONCLUSION: CHX dig and PA post-surface disinfection displayed a positive impact on bond strength with the radicular dentin. However, CPS and AS do not reveal any effect on the PBS when used for post-decontamination.

In Vitro Activity of Some Medicinal Plants on Blood Coagulation.

Objectives: The concern for finding natural and curative agents without adverse side effects has prompted the interest in discovering hemostatic agents from plants. Therefore, in vitro activity of Aizoon hispanicum L. (Aizoaceae), Centaurea hyalolepis Boiss. (Asteraceae), Heliotropium maris-mortui Zohary. (Boraginaceae), Parietaria judaica L. (Urticaceae), Polygonum arenarium Waldst. & Kit. (Polygonaceae), and Verbascum sinuatum L. (Scrophulariaceae) on blood coagulation was estimated by two common tests, which are the prothrombin time test (PT) and the activated partial thromboplastin time test (aPTT). Materials and Methods: The extracted powders from the plants under this study were adjusted to be 50 mg/mL. Then, in vitro effect of these extracts on the platelet poor plasma samples was measured by an automated coagulation analyzer using PT and aPTT tests. Results: Based on the obtained results, all plant extracts affected the coagulation cascade by rising either PT or aPTT or both, except for V. sinuatum extract, which reduced only aPTT value. Moreover, the recorded PT values showed that A. hispanicum, H. maris-mortui, and P. arenarium significantly prolonged the PT (p<0.05). Additionally, the results clearly showed that V. sinuatum acted as a coagulant agent based on aPTT values, while all other plants, in contrast, acted as strong anticoagulants. Among the plant species under study, A. hispanicum, H. maris-mortui, and P. arenarium extracts prolonged both PT and aPTT significantly (p<0.05). This could be referred to their additional effect on the common pathway. However, C. hyalolepis, P. judaica, and V. sinuatum showed no significant effect on PT values (p>0.05). Conclusion: The positive recorded data from this research could serve as identification of new hemostatic remedies that could be used for the commercial economic purposes and for managing several cardiovascular diseases.

Dental Students' Perception, Awareness and Knowledge About HPV Infection, Vaccine, and Its Association with Oral Cancer: A Multinational Study.

Background: Human papilloma virus (HPV) infection forms a major etiological factor for oropharyngeal cancer (OPC), which has exhibited increased global incidence. Aim: To compare the knowledge regarding HPV, its association with OPC, and HPV vaccine among students from different countries, years of the undergraduate program, and gender. Methods: The current multinational cross-sectional study was conducted in 886 undergraduate dental students from Egypt, India, Pakistan, Saudi Arabia, UAE, and Sudan through Google survey forms from July 2021 to September 2021. The survey form comprised 27 items divided into four sections. The answers to the questionnaire were compared among students from different countries, different years of the undergraduate program, and males and females. Chi-square test was used to evaluate the correlation between the demographic characteristics of students and their knowledge regarding HPV and OPC. Results: Females exhibited a better knowledge regarding knowledge and perception on HPV vaccine, whereas males exhibited a better knowledge regarding HPV and its correlation with OPC, and these differences were statistically significant (P < 0.05). The third- and fourth-year undergraduate students displayed a higher awareness of OPC and its connection with HPV than other year students, and this variance was found to be statistically significant (P < 0.001). Third-year and internship students exhibited a more positive attitude and comfort regarding the vaccine and discussing the same with patients than the other educational-level students. Students from India exhibited better knowledge about HPV and its association with OPC than the students from other countries, and this difference was statistically significant (P < 0.001). Conclusion: Disparities in knowledge regarding HPV-related oral cancer have been detected among the female and male participants among different nations. From the entire study population, Indian students exhibited better knowledge regarding HPV. Females from all the nations exhibited a more positive attitude and comfort regarding the vaccine and discussing the same with patients than males. The results of this necessitate intervention measures including training workshops and awareness campaigns. Improving their knowledge regarding the same may increase their awareness, resulting in better patient care.

COVID-19 Vaccine Hesitancy Associated With Vaccine Inequity Among Healthcare Workers in a Low-Income Fragile Nation.

Objectives: Preventing severe disease and acquiring population immunity to COVID-19 requires global immunization coverage through mass vaccination. While high-income countries are battling vaccine hesitancy, low-income and fragile nations are facing the double dilemma of vaccine hesitancy and lack of access to vaccines. There is inadequate information on any correlation between vaccine hesitancy and access to vaccines. Our study in a low-income nation aimed to fill this gap. Methods: In the backdrop of a severe shortage of COVID-19 vaccines in Yemen, a low-income fragile nation, we conducted a nation-wide cross-sectional survey among its healthcare workers (HCWs), between 6 July and 10 August 2021. We evaluated factors influencing agreement to accept a COVID-19 vaccine and any potential correlation between vaccine acceptance and lack of access to vaccines. Results: Overall, 61.7% (n = 975) of the 1,581 HCWs agreed to accept a COVID-19 vaccine. Only 45.4% of the participants agreed to have access to a COVID-19 vaccine, with no sex dependent variations. Although several determinants of vaccine acceptance were identified, including, having a systemic disease, following the updates about COVID-19 vaccines, complying with preventive guidelines, having greater anxiety about contracting COVID-19, previous infection with COVID-19, believing COVID-19 to be a severe disease, and lower concern about the side effects of COVID-19, the strongest was access to vaccines (OR: 3.18; 95% CI: 2.5-4.03; p-value: 0.001). Conclusion: The immediate and more dangerous threat in Yemen toward achieving population immunity is the severe shortage and lack of access to vaccines, rather than vaccine hesitancy, meaning, improving access to vaccines could lead to greater acceptance.

Noncarious cervical lesion pretreated using antimicrobial photodynamic therapy and diode laser in reducing dentin hypersensitivity bonded to different restorative material: Valuation of bond values and invitro dye leakage.

AIM: The present study aimed to appraise the effect of Diode laser (DL), riboflavin, and curcumin on the bond strength of adhesive restorative material and the effects of pretreatment on microleakage scores. MATERIAL AND METHODS: Ninety caries-free human permanent premolars were obtained and disinfected. All specimens were mounted till CEJ. To provide standardization, a 2 × 2 mm flat non-carious cervical lesion (NCCL) dentin surface was exposed. This was followed by dentin surface roughening/cervical groove preparation with a round bur. After tooth surface preparation, ninety specimens were divided arbitrarily into three groups. Group 1: NCCL exposed to DL; group 2: NCCL pretreated with riboflavin photosensitizer (RFP) and group 3 pretreated with curcumin photosensitizer (CP). All the three groups were further divided into two subgroups A1, A2, B1, B2, C1, and C2 based on the restorative material used (n = 15). Subgroup A1, B1, and C1 were restored with composite resin (CR). Subgroup A2, B2, and C2 were restored with RMGIC. Ten samples from each subgroup were evaluated for shear bond strength (SBS) testing under a universal testing machine (UTM). Five from each subgroup were evaluated for microleakage assessment. Bond strength and microleakage analysis were performed using analysis of variance (ANOVA) with a Post-hoc test (Tukey's post hoc test) at a significance level (p = 0.05). RESULTS: The group A1, DL-CR shows the highest SBS (16.41± 0.4 MPa). However, CP-RMGIC groups demonstrated the lowest bond integrity. RFP-CR and the DL-CR group displayed comparable outcomes of SBS (p>0.05). The highest microleakage was observed with CP-RMGIC. The least microleakage was displayed by DL-CR. CONCLUSION: Noncarious cervical lesions pretreated with diode laser and riboflavin photosensitizer showed better shear bond strength and reduced microleakage when bonded to composite resin than non-carious cervical lesions pretreated with curcumin.